1. General Information

1. Composition: Each 5ml ampoule contains Acetylcysteine 1000mg.
2. Form: Sterile injection.
3. Packaging: 5ml ampoule.

2. Product Introduction

Mucomelt 1000mg/5ml is a sterile injectable form of acetylcysteine, a powerful mucolytic agent. It helps to reduce the thickness of mucus and is widely used in respiratory and critical care for conditions involving mucus overproduction or toxicity management.

3. Uses

1. Management of respiratory conditions with excessive mucus, including:
2. Chronic obstructive pulmonary disease (COPD)
3. Bronchitis
4. Cystic fibrosis
5. As an antidote for paracetamol (acetaminophen) poisoning.

4. Benefits

1. Effectively reduces mucus viscosity, aiding in easier clearance.
2. Life-saving antidote for acute paracetamol overdose.
3. Provides rapid relief in respiratory obstruction caused by mucus buildup.

5. Side Effects

1. Common: Nausea, vomiting, rash.
2. Rare: Anaphylactic reactions, hypotension, bronchospasm.

6. Indication

1. Mucolytic therapy in respiratory conditions with viscous mucus.
2. Management of acetaminophen toxicity.

7. Contraindication

1. Hypersensitivity to acetylcysteine or its components.
2. Asthma patients, unless under careful supervision, due to the risk of bronchospasm.

8. How It Works

Acetylcysteine breaks disulfide bonds in mucus glycoproteins, reducing mucus viscosity and facilitating its clearance. In paracetamol toxicity, it replenishes glutathione stores, aiding in detoxification of the liver.

9. Substitute Medicine in Nepal

1. Inj Nacyst 1000mg/5ml
2. Inj NAC 1000mg/5ml